{"id":6185,"date":"2015-02-11T12:57:00","date_gmt":"2015-02-11T12:57:00","guid":{"rendered":"https:\/\/www.ipleiria.pt\/cursos\/?post_type=course&p=6185"},"modified":"2026-03-03T11:14:10","modified_gmt":"2026-03-03T11:14:10","slug":"undergraduate-in-biotechnology","status":"publish","type":"course","link":"https:\/\/www.ipleiria.pt\/en\/course\/undergraduate-in-biotechnology\/","title":{"rendered":"Biotechnology"},"content":{"rendered":"\n
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Biotechnology<\/h1>\n
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Course Type: <\/div>\n
Bachelor\u2019s Programme<\/div>\n <\/div>\n <\/div>\n\n\n
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Programme Introduction<\/h2>\n
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The degree in Biotechnology intends to give students solid scientific and technical expertise and comprehension in order to integrate the labor market for biotechnology-based companies (food processing, marine, pharmaceutical, environmental, or similar), as well as generate interest in pursuing studies at the 2nd cycle. Its multidisciplinary nature, including in the area of management, contributes to the development of skills that enable the development of entrepreneurial initiatives, as well as strengthen the link between applied research and commercialization of new products.<\/p>\n

A degree in Biotechnology aims to confer students with autonomy, critical thinking, communication skills and creativity, allowing them to successfully design and develop any professional project or scientific and technological research in the field of Biotechnology<\/p>\n<\/div>\n

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Programme Coordinator<\/h2>\n
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Alexandra Augusta Ramos Lopes da Cruz
alexandra.cruz@ipleiria.pt<\/a><\/p>\n<\/div>\n

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Reference\n<\/h2>\n
9016<\/div>\n
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School<\/h2>\n \n
Tourism and Maritime Technology<\/a><\/div>\n
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City<\/h2>\n \n
Peniche<\/a><\/div>\n
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Language<\/h2>\n
Portuguese<\/div>\n
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Type<\/h2>\n
Morning & Afternoon<\/div>\n
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Length<\/h2>\n
6 semesters<\/div>\n
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Vacancies\n<\/h2>\n
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General Contingent: 30
International Contingent: 3<\/p>\n<\/div>\n

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DGES certification<\/h2>\n
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Link to Registration<\/a><\/p>\n<\/div>\n

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Objectives<\/h2>\n
Programme<\/div>\n<\/div>\n
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This proposed study cycle provides students with the knowledge and technical and scientific skills to perform their duties and arouse interest in pursuing a scientific research or entrepreneurial career. The first semesters are organized to give basic and transversal skills within biotechnology, whereas in later semesters is given special emphasis to areas of specialization. Teamwork, autonomy, and communication to general public and peers skills will be developed through the discussion of case studies, presentations in oral, panel and report format of results of experimental and research work. At the end of the course students will develop a scientific project in biotechnology, inserted in R&D projects arising within the research unit recognized by FCT \u2013 GIRM \/ IPL.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><\/div><\/div><\/div>\n<\/div>\n<\/div>\n<\/div><\/div><\/div>\n\n\n\n

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Study Plan<\/h2>\n
ECTS: 180<\/div>\n <\/div>\n \n \n
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  1. 1st Year<\/li>\n
  2. 2nd Year<\/li>\n
  3. 3rd Year<\/li>\n <\/ol>\n
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    1st Year<\/caption>\n
    ID<\/th>\n Name<\/th>\n Semester<\/th>\n ECTS<\/th>\n Length<\/th>\n <\/tr>\n <\/thead>\n
    \n \n <\/td>\n \n \n Mathematics\n <\/a>\n <\/td>\n \n 1st Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
    \n
    1. Integral Calculus in IR
      1.1. Primitive: definition and properties; Primitivation Methods
      1.2. Defined integral: definition and properties; Fundamental theorem of integral calculus; Integral Calculus
      Applications<\/li>
    2. Differential Equations.
      2.1. Basic Concepts and Terminology
      2.2. 1st order ordinary EDs and arbitrary order linear ordinary EDs
      2.3. Applications.<\/li>
    3. Functions of Multiple Real Variables
      3.1. Definitions
      3.2. Partial derivatives
      3.3. Differentiability
      3.4. Extremes
      3.5 Multiple integrals (double and triple); Multiple integrals over limited regions
      3.6. Variable Change
      3.7. applications<\/li><\/ol>\n<\/td><\/tr>\n
    \n \n <\/td>\n \n \n Applied Physics\n <\/a>\n <\/td>\n \n 1st Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
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    1. Introduction<\/li>
    2. Classical Mechanics
      2.1. Kinetics; One-dimensional motion and circular motion;
      2.2. Dynamics: Newton’s Laws; Gravitational, frictional and inertial force;
      2.3. Work and Energy: work, power, kinetic energy and potential;
      2.4. Fluids: Pascal and Archimedes Principles, Bernoulli Equations, Laminar and Turbulent Flow;<\/li>
    3. Notions of Thermodynamics
      3.1. Zero law of thermodynamics, temperature, thermal equilibrium;
      3.2. First law of thermodynamics; Internal energy, Work, heat transfer;
      3.3. Second law of thermodynamics; Heat \/ work conversion; Carnot and entropy;<\/li>
    4. Notions of Electricity and Magnetism
      4.1. Electric Field, direct current, Ohm’s law;
      4.2. Magnetic and electromagnetic field, alternating current, electromagnetic waves.<\/li><\/ol>\n<\/td><\/tr>\n
    \n \n <\/td>\n \n \n Chemistry\n <\/a>\n <\/td>\n \n 1st Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
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    1. The chemical bond.<\/li>
    2. Intermolecular forces of solids, liquids and gases.<\/li>
    3. Chemical Kinetics:<\/li>
    4. Basics of Thermochemistry<\/li>
    5. Chemical Balance:<\/li>
    6. Acids and bases.<\/li><\/ol>\n<\/td><\/tr>\n
    \n \n <\/td>\n \n \n General Biology\n <\/a>\n <\/td>\n \n 1st Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
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    1. The Chemistry of Life<\/li>
    2. The cell
      2.1. Cell Theory and Cell Organization
      2.2. Organelles and the nucleus
      2.3. Membrane Structure and Function Cellular communication.<\/li>
    3. Characterization of Biological Diversity<\/li>
    4. Ecological diversity and biogeography<\/li>
    5. General patterns of variation in biological diversity<\/li><\/ol>\n<\/td><\/tr>\n
    \n \n <\/td>\n \n \n Laboratories of Biotechnology I\n <\/a>\n <\/td>\n \n 1st Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
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    1. Chemical and biotechnology laboratories
      1.1. Laboratory health and safety; Chemical, electrical, radiological and fire safety.
      1.2. Chemical waste management.<\/li>
    2. Scientific Method
      2.1. Experimental design and basic laboratory procedures
      2.2. Data Organization<\/li>
    3. Validation of analytical methods<\/li>
    4. Research, Elaboration and Results Communication<\/li>
    5. Classical methods of analysis<\/li>
    6. Instrumental methods of analysis – Refractometry; Spectrophotometry; Potentiometry and Chromatography<\/li>
    7. Chemical methods applied in bioseparation, concentration and purification processes.<\/li>
    8. Process integration and scaling up.<\/li><\/ol>\n<\/td><\/tr>\n
    \n \n <\/td>\n \n \n Numerical Methods and Computation\n <\/a>\n <\/td>\n \n 2nd Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
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    1. Basics of algorithms and computation.<\/li>
    2. Successions and convergence<\/li>
    3. Representation of numbers and errors.<\/li>
    4. Polynomial interpolation.<\/li>
    5. Numerical integration.<\/li>
    6. Nonlinear Equations.<\/li>
    7. Matrices and systems of linear equations.<\/li><\/ol>\n<\/td><\/tr>\n
    \n \n <\/td>\n \n \n Biochemistry I\n <\/a>\n <\/td>\n \n 2nd Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
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    1. Introduction – Concept and scope of biochemistry.<\/li>
    2. Macromolecule chemistry.<\/li>
    3. Proteins<\/li>
    4. Nucleic acids<\/li>
    5. Enzymes<\/li>
    6. Glycerides<\/li>
    7. Lipids<\/li>
    8. Vitamins<\/li><\/ol>\n<\/td><\/tr>\n
    \n \n <\/td>\n \n \n Bioprocesses I\n <\/a>\n <\/td>\n \n 2nd Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
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    1 – Introduction to industrial processes
    2 – System concept, intensive and extensive properties<\/p>\n\n\n\n

    1. Mass Conservation Law<\/li>
    2. Mass Balances<\/li>
    3. Thermodynamics
      6 – Energy Balances
      7 – Fundamentals of fluid mechanics
      8 – Fundamentals of heat and mass transfer.
      9- Biotechnological Process Flowcharts
      10 \u2013Income
      11 – Case Studies in Biotechnology.<\/li><\/ol>\n<\/td><\/tr>\n
    \n \n <\/td>\n \n \n Microbiology I\n <\/a>\n <\/td>\n \n 2nd Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
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    1. Introduction to microbiology<\/li>
    2. Nutrition, Growth and Control of Microorganisms
      2.1. Culture and isolation
      2.2. Growth kinetics and factors affecting growth
      2.3. Growth control and death kinetics<\/li>
    3. Prokaryotic metabolism:
      3.1. Definitions and Importance of prokaryotes in biogeochemical cycles
      3.2. Heterotrophic, lithotrophic and autotrophic metabolism
      3.3. Biosynthesis<\/li>
    4. Viruses:
      4.1. Structure and general characteristics
      4.2. Virus Reproduction and Culture<\/li>
    5. Applied Microbiology:
      5.1. Top Microbiology Products of Interest to Man<\/li><\/ol>\n<\/td><\/tr>\n
    \n \n <\/td>\n \n \n Laboratories of Biotechnology II\n <\/a>\n <\/td>\n \n 2nd Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
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    1. Biology and biotechnology laboratories<\/li>
    2. 1.1. Assessment and classification of biological risks and hierarchy of containment levels.<\/li>
    3. 1.2. Biological Protection and Safety Equipment Directives<\/li>
    4. 1.3. Accidents and Incidents; Biological Waste Management<\/li>
    5. Planning, collection, conservation and treatment of biological samples<\/li>
    6. Methods of preparation and analysis of biological samples.<\/li>
    7. Optical microscopy.<\/li>
    8. Sterile techniques.<\/li>
    9. Basic techniques in molecular biology<\/li>
    10. Biological methods applied in bioseparation processes and monitoring of isolation and purification processes<\/li><\/ol>\n<\/td><\/tr>\n <\/tbody>\n <\/table>\n <\/div>\n <\/div>\n
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      2nd Year<\/caption>\n
      ID<\/th>\n Name<\/th>\n Semester<\/th>\n ECTS<\/th>\n Length<\/th>\n <\/tr>\n <\/thead>\n
      \n \n <\/td>\n \n \n Molecular Biology\n <\/a>\n <\/td>\n \n 1st Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
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      P1. DNA and RNA structure. Chromosomes, chromatin and nucleosome.
      P2. DNA Replication
      P3. Mutations and DNA repair mechanisms.
      P4. Genetic recombination.
      P5. RNA transcription and processing.
      P6. MRNA translation.
      P7. Regulation of gene expression<\/p>\n<\/td><\/tr>\n

      \n \n <\/td>\n \n \n Biostatistics\n <\/a>\n <\/td>\n \n 1st Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
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      1. Introduction to Statistics and Biostatistics.<\/li>
      2. Descriptive Statistics<\/li>
      3. Random Variables<\/li>
      4. Statistical Inference<\/li>
      5. Correlation and Regression<\/li><\/ol>\n<\/td><\/tr>\n
      \n \n <\/td>\n \n \n Biochemistry II\n <\/a>\n <\/td>\n \n 1st Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
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      1. Introduction to metabolism<\/li>
      2. Glycid metabolism
        2.1. Regulation of glycemic metabolism<\/li>
      3. Citric acid cycle and glyoxylate cycle
        3.1. Regulation of citric acid cycle and glyoxylate cycle metabolism<\/li>
      4. Oxidative phosphorylation
        4.1. Regulation of oxidative phosphorylation.<\/li>
      5. Photosynthesis<\/li>
      6. Fatty acid metabolism
        6.1. Regulation of fatty acid metabolism<\/li>
      7. Protein Metabolism<\/li><\/ol>\n<\/td><\/tr>\n
      \n \n <\/td>\n \n \n Bioprocesses II\n <\/a>\n <\/td>\n \n 1st Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
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      1. Background: Biotechnology and Bioprocess Engineering<\/li>
      2. Bioreactors
        2.1. Stoichiometry and kinetics of microbial processes
        2.2. Type geometries and modes of operation in bioreactors;
        2.3. Mixing and Shaking; Mass transfer, heat transfer and sterilization
        2.4. Scale up and Scale down<\/li>
      3. Bioseparation Processes<\/li>
      4. Biocatalysis
        4.1. Enzymatic Kinetics
        4.2. Cellular enzymes and biocatalysts and immobilization methods.
        4.3. Biocatalysis in unconventional media.<\/li><\/ol>\n<\/td><\/tr>\n
      \n \n <\/td>\n \n \n Microbiology II\n <\/a>\n <\/td>\n \n 1st Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
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      [P1.] Introduction: scope of microbiology applied to Biotechnology; industrial microbiology versus biotechnology
      [P2.] Groups of microorganisms most important in industrial microbiology \/ biotechnology
      [P3.] Basic requirements of microorganisms: culture media; carbon and nitrogen sources; alternative raw materials.
      [P4.] Fermentative processes; upstream and downstream processisng.
      [P5.] Microbiology as a tool in different areas of biotechnology: food, environmental, industrial, marine.<\/p>\n<\/td><\/tr>\n

      \n \n <\/td>\n \n \n Genetic Engineering\n <\/a>\n <\/td>\n \n 2nd Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
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      1. Introduction to genetic engineering<\/li>
      2. Vectors<\/li>
      3. Enzymes in genetic engineering
        3.1. Restriction enzymes, endo and exonucleases, classification and modes of action
        3.2. DNases, Rases, methylases, phosphatases, kinases, ligases<\/li>
      4. DNA hybridization, amplification and sequencing
        4.1. DNA detection methods, polymerase chain reaction (PCR), PCR variations and their applications
        4.2. Nucleic acid hybridization methods.<\/li>
      5. DNA library construction
        5.1. DNA isolation, purification and quantification, plasmid isolation
        5.2. Construction of cDNA and genomic DNA libraries<\/li>
      6. Gene Transfer Techniques
        6.1. Plant gene transfer techniques (Agrobacterium and plant virus mediated gene transfer), animals and
        microorganisms
        6.2. Transformation, electroporation, microprojectiles<\/li>
      7. Applications
        7.1. Microbial Biotechnology
        7.2. Gene Therapy<\/li><\/ol>\n<\/td><\/tr>\n
      \n \n <\/td>\n \n \n Environmental Biotechnology\n <\/a>\n <\/td>\n \n 2nd Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
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      1. Pollution and contamination<\/li>
      2. Environmental Risk Assessment<\/li>
      3. Fundamental Concepts<\/li>
      4. Bioremediation.<\/li>
      5. Biotechnological applications for sustainable processes.<\/li>
      6. Methods of treatment of liquid and gaseous effluents and waste.<\/li>
      7. Environmental and waste management legislation.<\/li><\/ol>\n<\/td><\/tr>\n
      \n \n <\/td>\n \n \n Food Biotechnology\n <\/a>\n <\/td>\n \n 2nd Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
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      1. Introductory Concepts of Food Biotechnology. Evolution of Biotechnology in the Food Industry<\/li>
      2. Microorganisms involved in food fermentations.<\/li>
      3. Fermentative Food Processes
        3.2 Use of yeast
        3.3 Use of bacteria<\/li>
      4. Sensory Analysis<\/li>
      5. Functional Foods<\/li>
      6. Application and production of enzymes in the food industry.<\/li>
      7. Technologies for the production and application of genetically modified organisms (GMOs).<\/li><\/ol>\n<\/td><\/tr>\n
      \n \n <\/td>\n \n \n Pharmaceutical Biotechnology\n <\/a>\n <\/td>\n \n 2nd Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
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      1 – Fundamental concepts and application areas of Pharmaceutical Biotechnology.
      2 – Fundamental research lines in pharmaceutical biotechnology.
      2.1 Production of recombinant therapeutic molecules: small molecules and natural products, hormones and cytokines,
      enzymes.
      2.2 Monoclonal antibodies (therapeutic and diagnostic) and vaccines.
      2.3 Gene and cellular therapy.
      2.4 Biomaterials and tissue engineering.
      2.5 Application in diagnosis.
      3 – Industrial development, production process and validation of new biopharmaceuticals. Biosynthesis of drugs by
      fermentation and bio-transformation.
      4 – Legislative and economic considerations. Future perspectives.<\/p>\n<\/td><\/tr>\n

      \n \n <\/td>\n \n \n Marine Biotechnology I\n <\/a>\n <\/td>\n \n 2nd Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
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      1. Marine microbiology
        1.1 Introduction to marine microbiology
        1.2 Methods in marine microbiology
        1.3 Physiology of marine microorganisms
        1.4 Role of microorganisms in oceanic processes
        1.5 Genomics of marine microorganisms<\/li>
      2. Marine bioprospecting
        2.1 Isolation of marine natural products
        2.2 Bioactive and biomaterial compounds of the marine environment
        2.3 Assays for detection of enzymes and bioactive molecules<\/li>
      3. Sustainable growth of marine organisms
        3.1 Microalgae and macroalgae cultivation
        3.2 Cultivation of other marine organisms<\/li><\/ol>\n<\/td><\/tr>\n <\/tbody>\n <\/table>\n <\/div>\n <\/div>\n
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        \n \n \n \n \n \n \n \n \n \n \n \n \n
        3rd Year<\/caption>\n
        ID<\/th>\n Name<\/th>\n Semester<\/th>\n ECTS<\/th>\n Length<\/th>\n <\/tr>\n <\/thead>\n
        \n \n <\/td>\n \n \n Bioinformatics\n <\/a>\n <\/td>\n \n 1st Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
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        Q1. Biological databases.
        P2. Introduction to algorithms in bioinformatics.
        P3. Sequence alignment, simple alignment, multiple alignment.
        Q4. Phylogeny
        Q4. Motif prediction and protein structure.
        P5. Gene prediction and genomic annotation.
        P6. Gene expression analysis<\/p>\n<\/td><\/tr>\n

        \n \n <\/td>\n \n \n Imunology and Biomedicine\n <\/a>\n <\/td>\n \n 1st Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
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        1. Introduction to immunology. Cells and organs of the immune system.<\/li>
        2. T cells and B cells: selection, maturation and activation.<\/li>
        3. Specific and non-specific defense mechanisms.
          3.1.Inflammatory response. Complement system. Interferon.
          3.2. Cellular immunity and humoral immunity.<\/li>
        4. Major histocompatibility complex: heredity, processing and antigen presentation.<\/li>
        5. Immunization.<\/li>
        6. Pathophysiology of the immune system: health and disease.
          6.1.Inflammation and anti-inflammatory mediators.
          6.2.Tolerance, hypersensitivity and autoimmunity; Immunodeficiencies.
          6.3. Transplantation and immune base of rejection.
          6.4.Cancer and immune system.
          6.5.Immunomodulation and immunotherapy.<\/li>
        7. Antigens and immunogens.<\/li><\/ol>\n<\/td><\/tr>\n
        \n \n <\/td>\n \n \n Animal Cell Technology\n <\/a>\n <\/td>\n \n 1st Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
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        1. Basic principles of animal cell and tissue culture.<\/li>
        2. Asepsis techniques and sterilization methods. Basic methods in cell and tissue culture: culture medium, subculture,
          cell viability.
          3.Culture of animal cells and tissues: Animal cell biology: metabolism; accession; proliferation; differentiation. Primary
          culture, subcultures and cell lines. Equipment and culture media. Cryopreservation of animal cells. Experimental
          methods: cell viability; cell proliferation; Apoptosis Tissue engineering.<\/li>
        3. Stem Cells<\/li>
        4. Multidrug Resistant Cells: Model Used to Test New Drugs<\/li>
        5. Animal models for tumor tissue induction.<\/li><\/ol>\n<\/td><\/tr>\n
        \n \n <\/td>\n \n \n Plant Cell Technology\n <\/a>\n <\/td>\n \n 1st Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
        \n
        1. Basic principles of plant cell and tissue culture: historical perspective and study methods in plant biotechnology.<\/li>
        2. In vitro plant culture: totipotence and competence; vegetative multiplication, growth regulators, culture media and
          environmental conditions of culture. Plant cloning – meristema propagation and organogenesis: meristema types,
          objectives and limitations.<\/li>
        3. Cell suspensions and somatic embryogenesis: types of embryogenesis, phases and induction. Pollen
          embryogenesis and haploid production. Cell suspensions and production of secondary metabolites. Protoplasts and
          somatic hybridization.<\/li>
        4. Genetic manipulation and plant breeding. Genetically modified plants<\/li><\/ol>\n<\/td><\/tr>\n
        \n \n <\/td>\n \n \n Marine Biotechnology II\n <\/a>\n <\/td>\n \n 1st Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
        \n
        1. Seaweed Processes and Products<\/li>
        2. Biomaterials<\/li>
        3. Biosensors<\/li>
        4. Biomarkers<\/li>
        5. Biofuels<\/li>
        6. Bioremediation Applications<\/li>
        7. Biotechnological interventions in aquaculture<\/li><\/ol>\n<\/td><\/tr>\n
        \n \n <\/td>\n \n \n Biotechnology in Society\n <\/a>\n <\/td>\n \n 2nd Semester\n <\/td>\n \n 6\n <\/td>\n \n 60 h\n <\/td>\n <\/tr>\n
        \n
        1. Bioethics<\/li>
        2. Communication in Science<\/li>
        3. Biotechnology Entrepreneurship<\/li>
        4. Intellectual Property<\/li>
        5. Scientific Careers<\/li>
        6. National and European Support Programs<\/li>
        7. Regulatoty Framework<\/li>
        8. Organization of study visit, lecture or scientific workshop<\/li><\/ol>\n<\/td><\/tr>\n
        \n \n <\/td>\n \n \n Interdisciplinary Project\n <\/a>\n <\/td>\n \n 2nd Semester\n <\/td>\n \n 9\n <\/td>\n \n 90 h\n <\/td>\n <\/tr>\n
        \n
        1. Theme selection and work team<\/li>
        2. Research and experimental design<\/li>
        3. Development of laboratory work<\/li>
        4. Analysis and treatment of results<\/li>
        5. Presentation and public discussion of the work developed<\/li><\/ol>\n<\/td><\/tr>\n
        \n \n <\/td>\n \n \n Project\/Intership\n <\/a>\n <\/td>\n \n 2nd Semester\n <\/td>\n \n 15\n <\/td>\n \n \n <\/td>\n <\/tr>\n
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        Project<\/p>\n\n\n\n

        1. Research and update the state of the art on the theme
          1.1. Literature search in the area of biotechnology
          1.2. Prepare a monograph about the state of art of a given area of biotechnology<\/li>
        2. Planning and development of a scientific project in Biotechnology
          2.1. Definition of working hypotheses
          2.2. Drafting and planning the steps in the development of a project
          2.3. Organizing the work in the laboratory
          2.4. Presentation of the preliminary scientific project in the form of seminars.
          2.5. Planning of the experimental design.
          2.6. Presentation of preliminary results of the scientific project in the form of a seminar.<\/li>
        3. Writing the final report.
          3.1. Writing a report with proper structure \/ formatting and discussion of the results obtained comparing them to the current state of the art.<\/li>
        4. Presentation and discussion of final project
          4.1. Defence and discussion of the written report and the oral presentation of the proposed project<\/li><\/ol>\n\n\n\n

          Internship<\/p>\n\n\n\n

          The Areas \/ Functions eligible for the internship are all related to the Biotechnology topics covered in the other
          curricular units of the degree and which fit the requirements of the regulation of curricular and extracurricular
          internships of ESTM (Regulation No. 1087\/2016).
          According to each specific company, the registration \/ participation in the tasks should pay attention to the following
          aspects:<\/p>\n\n\n\n

          1. Research and update the state of the art on the topic proposed in the work plan.<\/li>
          2. Requirements, challenges and particular aspects of the scope of activities performed<\/li>
          3. Report writing<\/li><\/ol>\n<\/td><\/tr>\n <\/tbody>\n <\/table>\n <\/div>\n <\/div>\n <\/div>\n \n
            \n \n <\/span>\n Previous Year<\/span>\n <\/a>\n \n <\/span>\n Next Year<\/span>\n <\/a>\n <\/div>\n <\/div>\n <\/div>\n <\/section>\n\n\n\n
            <\/div>\n\n\n\n
            \n\n\n\n
            <\/div>\n\n\n\n
            \n
            \n

            Entry Requirements<\/h2>\n
            \n

            For further\u00a0information about international students’ applications,
            please see International Applicants<\/a> or contact\u00a0the International Students’ Office by email: studywithus@ipleiria.pt<\/a><\/p>\n<\/div>\n

            <\/div>\n<\/div><\/div>\n\n\n\n
            <\/div>\n\n\n\n
            \n

            Accreditation<\/h2>\n
            \n

            State: Accreditated
            N\u00ba years of Accredidation: 6
            Date of Publication: 02\/09\/2021
            A3ES Accreditation<\/a><\/p>\n<\/div>\n

            <\/div>\n<\/div>\n\n<\/div>\n<\/div>\n\n\n\n
            <\/div>\n\n\n
            \n
            <\/div>\n
            <\/div>\n
            \n
            \n

            Online Application<\/h2>\n

            Use the button bellow to start your application.<\/p> \n

            \n
            \n How to apply<\/a>\n \n <\/div>\n <\/div>\n <\/div>\n <\/div>\n<\/div>\n\n\n\n
            <\/div>
            \n
            \n
            \n

            Application Fee<\/h2>\n
            \n

            60\u20ac<\/p>\n<\/div>\n

            <\/div>\n<\/div><\/div>\n\n\n\n
            \n

            Enrolment Fee<\/h2>\n
            \n

            General Contingent: 30\u20ac
            International Contingent: 100\u20ac<\/p>\n<\/div>\n

            <\/div>\n<\/div><\/div>\n\n\n\n
            \n

            Tuition Fee<\/h2>\n
            \n

            General Contingent: 697 \u20ac
            International Contingent: 3000\u20ac<\/p>\n<\/div>\n

            <\/div>\n<\/div><\/div>\n<\/div>\n<\/div><\/div><\/div>\n\n\n\n
            <\/div>\n\n\n\n
            \n\n\n \n\n
            \n
            \"\"<\/figure><\/div>","protected":false},"featured_media":25046,"template":"","meta":{"multilingual_post_translation":"{\"pt-PT\":{\"url\":\"https:\/\/www.ipleiria.pt\/curso\/licenciatura-em-biotecnologia\/\",\"postID\":6185,\"postTitle\":\"Licenciatura em Biotecnologia\",\"siteID\":1,\"customURL\":false,\"languageInfo\":{\"multilingual_site_api_url\":\"https:\/\/www.ipleiria.pt\/wp-json\/\",\"name\":\"Portugu\u00eas\",\"locale\":\"pt_PT\"}}}","custompostfields_meta-description":"","custompostfields_course_presentation":"\n

            The degree in Biotechnology intends to give students solid scientific and technical expertise and comprehension in order to integrate the labor market for biotechnology-based companies (food processing, marine, pharmaceutical, environmental, or similar), as well as generate interest in pursuing studies at the 2nd cycle. Its multidisciplinary nature, including in the area of management, contributes to the development of skills that enable the development of entrepreneurial initiatives, as well as strengthen the link between applied research and commercialization of new products.<\/p>\n

            A degree in Biotechnology aims to confer students with autonomy, critical thinking, communication skills and creativity, allowing them to successfully design and develop any professional project or scientific and technological research in the field of Biotechnology<\/p>\n","custompostfields_course_content":"","custompostfields_course_code":"9016","custompostfields_course_public_notice":"","custompostfields_course_length":"6 semesters","custompostfields_course_ects":"180","custompostfields_course_supervisor":"\n

            Alexandra Augusta Ramos Lopes da Cruz
            alexandra.cruz@ipleiria.pt<\/a><\/p>\n","custompostfields_course_vacancies":"\n

            General Contingent: 30
            International Contingent: 3<\/p>\n","custompostfields_course_application_fee":"\n

            60\u20ac<\/p>\n","custompostfields_course_enrolment_fee":"\n

            General Contingent: 30\u20ac
            International Contingent: 100\u20ac<\/p>\n","custompostfields_course_tuition_fee":"\n

            General Contingent: 697 \u20ac
            International Contingent: 3000\u20ac<\/p>\n","custompostfields_course_goals":"\n

            \n
            \n
            \n
            \n
            \n

            This proposed study cycle provides students with the knowledge and technical and scientific skills to perform their duties and arouse interest in pursuing a scientific research or entrepreneurial career. The first semesters are organized to give basic and transversal skills within biotechnology, whereas in later semesters is given special emphasis to areas of specialization. Teamwork, autonomy, and communication to general public and peers skills will be developed through the discussion of case studies, presentations in oral, panel and report format of results of experimental and research work. At the end of the course students will develop a scientific project in biotechnology, inserted in R&D projects arising within the research unit recognized by FCT \u2013 GIRM \/ IPL.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","custompostfields_course_future_studies":"","custompostfields_course_career_prospects":"","custompostfields_course_entry_requirements":"\n

            For further\u00a0information about international students' applications,
            please see             International Applicants<\/a> or contact\u00a0the International Students' Office by email: studywithus@ipleiria.pt<\/a><\/p>\n","custompostfields_course_more_information":"","custompostfields_course_curriculum":"[{\"curricular_plan_section_title\":\"1st Year\",\"curricular_plan_cus\":[{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Mathematics\",\"curricular_plan_cu_period\":\"1st Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n

            1. Integral Calculus in IR
              1.1. Primitive: definition and properties; Primitivation Methods
              1.2. Defined integral: definition and properties; Fundamental theorem of integral calculus; Integral Calculus
              Applications<\/li>
            2. Differential Equations.
              2.1. Basic Concepts and Terminology
              2.2. 1st order ordinary EDs and arbitrary order linear ordinary EDs
              2.3. Applications.<\/li>
            3. Functions of Multiple Real Variables
              3.1. Definitions
              3.2. Partial derivatives
              3.3. Differentiability
              3.4. Extremes
              3.5 Multiple integrals (double and triple); Multiple integrals over limited regions
              3.6. Variable Change
              3.7. applications<\/li><\/ol>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Applied Physics\",\"curricular_plan_cu_period\":\"1st Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n
              1. Introduction<\/li>
              2. Classical Mechanics
                2.1. Kinetics; One-dimensional motion and circular motion;
                2.2. Dynamics: Newton's Laws; Gravitational, frictional and inertial force;
                2.3. Work and Energy: work, power, kinetic energy and potential;
                2.4. Fluids: Pascal and Archimedes Principles, Bernoulli Equations, Laminar and Turbulent Flow;<\/li>
              3. Notions of Thermodynamics
                3.1. Zero law of thermodynamics, temperature, thermal equilibrium;
                3.2. First law of thermodynamics; Internal energy, Work, heat transfer;
                3.3. Second law of thermodynamics; Heat \/ work conversion; Carnot and entropy;<\/li>
              4. Notions of Electricity and Magnetism
                4.1. Electric Field, direct current, Ohm's law;
                4.2. Magnetic and electromagnetic field, alternating current, electromagnetic waves.<\/li><\/ol>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Chemistry\",\"curricular_plan_cu_period\":\"1st Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n
                1. The chemical bond.<\/li>
                2. Intermolecular forces of solids, liquids and gases.<\/li>
                3. Chemical Kinetics:<\/li>
                4. Basics of Thermochemistry<\/li>
                5. Chemical Balance:<\/li>
                6. Acids and bases.<\/li><\/ol>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"General Biology\",\"curricular_plan_cu_period\":\"1st Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n
                  1. The Chemistry of Life<\/li>
                  2. The cell
                    2.1. Cell Theory and Cell Organization
                    2.2. Organelles and the nucleus
                    2.3. Membrane Structure and Function Cellular communication.<\/li>
                  3. Characterization of Biological Diversity<\/li>
                  4. Ecological diversity and biogeography<\/li>
                  5. General patterns of variation in biological diversity<\/li><\/ol>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Laboratories of Biotechnology I\",\"curricular_plan_cu_period\":\"1st Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n
                    1. Chemical and biotechnology laboratories
                      1.1. Laboratory health and safety; Chemical, electrical, radiological and fire safety.
                      1.2. Chemical waste management.<\/li>
                    2. Scientific Method
                      2.1. Experimental design and basic laboratory procedures
                      2.2. Data Organization<\/li>
                    3. Validation of analytical methods<\/li>
                    4. Research, Elaboration and Results Communication<\/li>
                    5. Classical methods of analysis<\/li>
                    6. Instrumental methods of analysis - Refractometry; Spectrophotometry; Potentiometry and Chromatography<\/li>
                    7. Chemical methods applied in bioseparation, concentration and purification processes.<\/li>
                    8. Process integration and scaling up.<\/li><\/ol>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Numerical Methods and Computation\",\"curricular_plan_cu_period\":\"2nd Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n
                      1. Basics of algorithms and computation.<\/li>
                      2. Successions and convergence<\/li>
                      3. Representation of numbers and errors.<\/li>
                      4. Polynomial interpolation.<\/li>
                      5. Numerical integration.<\/li>
                      6. Nonlinear Equations.<\/li>
                      7. Matrices and systems of linear equations.<\/li><\/ol>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Biochemistry I\",\"curricular_plan_cu_period\":\"2nd Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n
                        1. Introduction - Concept and scope of biochemistry.<\/li>
                        2. Macromolecule chemistry.<\/li>
                        3. Proteins<\/li>
                        4. Nucleic acids<\/li>
                        5. Enzymes<\/li>
                        6. Glycerides<\/li>
                        7. Lipids<\/li>
                        8. Vitamins<\/li><\/ol>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Bioprocesses I\",\"curricular_plan_cu_period\":\"2nd Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n

                          1 - Introduction to industrial processes
                          2 - System concept, intensive and extensive properties<\/p>\\n\\n\\n\\n

                          1. Mass Conservation Law<\/li>
                          2. Mass Balances<\/li>
                          3. Thermodynamics
                            6 - Energy Balances
                            7 - Fundamentals of fluid mechanics
                            8 - Fundamentals of heat and mass transfer.
                            9- Biotechnological Process Flowcharts
                            10 \u2013Income
                            11 - Case Studies in Biotechnology.<\/li><\/ol>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Microbiology I\",\"curricular_plan_cu_period\":\"2nd Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n
                            1. Introduction to microbiology<\/li>
                            2. Nutrition, Growth and Control of Microorganisms
                              2.1. Culture and isolation
                              2.2. Growth kinetics and factors affecting growth
                              2.3. Growth control and death kinetics<\/li>
                            3. Prokaryotic metabolism:
                              3.1. Definitions and Importance of prokaryotes in biogeochemical cycles
                              3.2. Heterotrophic, lithotrophic and autotrophic metabolism
                              3.3. Biosynthesis<\/li>
                            4. Viruses:
                              4.1. Structure and general characteristics
                              4.2. Virus Reproduction and Culture<\/li>
                            5. Applied Microbiology:
                              5.1. Top Microbiology Products of Interest to Man<\/li><\/ol>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Laboratories of Biotechnology II\",\"curricular_plan_cu_period\":\"2nd Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n
                              1. Biology and biotechnology laboratories<\/li>
                              2. 1.1. Assessment and classification of biological risks and hierarchy of containment levels.<\/li>
                              3. 1.2. Biological Protection and Safety Equipment Directives<\/li>
                              4. 1.3. Accidents and Incidents; Biological Waste Management<\/li>
                              5. Planning, collection, conservation and treatment of biological samples<\/li>
                              6. Methods of preparation and analysis of biological samples.<\/li>
                              7. Optical microscopy.<\/li>
                              8. Sterile techniques.<\/li>
                              9. Basic techniques in molecular biology<\/li>
                              10. Biological methods applied in bioseparation processes and monitoring of isolation and purification processes<\/li><\/ol>\\n\"}]},{\"curricular_plan_section_title\":\"2nd Year\",\"curricular_plan_cus\":[{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Molecular Biology\",\"curricular_plan_cu_period\":\"1st Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n

                                P1. DNA and RNA structure. Chromosomes, chromatin and nucleosome.
                                P2. DNA Replication
                                P3. Mutations and DNA repair mechanisms.
                                P4. Genetic recombination.
                                P5. RNA transcription and processing.
                                P6. MRNA translation.
                                P7. Regulation of gene expression<\/p>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Biostatistics\",\"curricular_plan_cu_period\":\"1st Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n

                                1. Introduction to Statistics and Biostatistics.<\/li>
                                2. Descriptive Statistics<\/li>
                                3. Random Variables<\/li>
                                4. Statistical Inference<\/li>
                                5. Correlation and Regression<\/li><\/ol>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Biochemistry II\",\"curricular_plan_cu_period\":\"1st Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n
                                  1. Introduction to metabolism<\/li>
                                  2. Glycid metabolism
                                    2.1. Regulation of glycemic metabolism<\/li>
                                  3. Citric acid cycle and glyoxylate cycle
                                    3.1. Regulation of citric acid cycle and glyoxylate cycle metabolism<\/li>
                                  4. Oxidative phosphorylation
                                    4.1. Regulation of oxidative phosphorylation.<\/li>
                                  5. Photosynthesis<\/li>
                                  6. Fatty acid metabolism
                                    6.1. Regulation of fatty acid metabolism<\/li>
                                  7. Protein Metabolism<\/li><\/ol>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Bioprocesses II\",\"curricular_plan_cu_period\":\"1st Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n
                                    1. Background: Biotechnology and Bioprocess Engineering<\/li>
                                    2. Bioreactors
                                      2.1. Stoichiometry and kinetics of microbial processes
                                      2.2. Type geometries and modes of operation in bioreactors;
                                      2.3. Mixing and Shaking; Mass transfer, heat transfer and sterilization
                                      2.4. Scale up and Scale down<\/li>
                                    3. Bioseparation Processes<\/li>
                                    4. Biocatalysis
                                      4.1. Enzymatic Kinetics
                                      4.2. Cellular enzymes and biocatalysts and immobilization methods.
                                      4.3. Biocatalysis in unconventional media.<\/li><\/ol>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Microbiology II\",\"curricular_plan_cu_period\":\"1st Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n

                                      [P1.] Introduction: scope of microbiology applied to Biotechnology; industrial microbiology versus biotechnology
                                      [P2.] Groups of microorganisms most important in industrial microbiology \/ biotechnology
                                      [P3.] Basic requirements of microorganisms: culture media; carbon and nitrogen sources; alternative raw materials.
                                      [P4.] Fermentative processes; upstream and downstream processisng.
                                      [P5.] Microbiology as a tool in different areas of biotechnology: food, environmental, industrial, marine.<\/p>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Genetic Engineering\",\"curricular_plan_cu_period\":\"2nd Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n

                                      1. Introduction to genetic engineering<\/li>
                                      2. Vectors<\/li>
                                      3. Enzymes in genetic engineering
                                        3.1. Restriction enzymes, endo and exonucleases, classification and modes of action
                                        3.2. DNases, Rases, methylases, phosphatases, kinases, ligases<\/li>
                                      4. DNA hybridization, amplification and sequencing
                                        4.1. DNA detection methods, polymerase chain reaction (PCR), PCR variations and their applications
                                        4.2. Nucleic acid hybridization methods.<\/li>
                                      5. DNA library construction
                                        5.1. DNA isolation, purification and quantification, plasmid isolation
                                        5.2. Construction of cDNA and genomic DNA libraries<\/li>
                                      6. Gene Transfer Techniques
                                        6.1. Plant gene transfer techniques (Agrobacterium and plant virus mediated gene transfer), animals and
                                        microorganisms
                                        6.2. Transformation, electroporation, microprojectiles<\/li>
                                      7. Applications
                                        7.1. Microbial Biotechnology
                                        7.2. Gene Therapy<\/li><\/ol>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Environmental Biotechnology\",\"curricular_plan_cu_period\":\"2nd Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n
                                        1. Pollution and contamination<\/li>
                                        2. Environmental Risk Assessment<\/li>
                                        3. Fundamental Concepts<\/li>
                                        4. Bioremediation.<\/li>
                                        5. Biotechnological applications for sustainable processes.<\/li>
                                        6. Methods of treatment of liquid and gaseous effluents and waste.<\/li>
                                        7. Environmental and waste management legislation.<\/li><\/ol>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Food Biotechnology\",\"curricular_plan_cu_period\":\"2nd Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n
                                          1. Introductory Concepts of Food Biotechnology. Evolution of Biotechnology in the Food Industry<\/li>
                                          2. Microorganisms involved in food fermentations.<\/li>
                                          3. Fermentative Food Processes
                                            3.2 Use of yeast
                                            3.3 Use of bacteria<\/li>
                                          4. Sensory Analysis<\/li>
                                          5. Functional Foods<\/li>
                                          6. Application and production of enzymes in the food industry.<\/li>
                                          7. Technologies for the production and application of genetically modified organisms (GMOs).<\/li><\/ol>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Pharmaceutical Biotechnology\",\"curricular_plan_cu_period\":\"2nd Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n

                                            1 - Fundamental concepts and application areas of Pharmaceutical Biotechnology.
                                            2 - Fundamental research lines in pharmaceutical biotechnology.
                                            2.1 Production of recombinant therapeutic molecules: small molecules and natural products, hormones and cytokines,
                                            enzymes.
                                            2.2 Monoclonal antibodies (therapeutic and diagnostic) and vaccines.
                                            2.3 Gene and cellular therapy.
                                            2.4 Biomaterials and tissue engineering.
                                            2.5 Application in diagnosis.
                                            3 - Industrial development, production process and validation of new biopharmaceuticals. Biosynthesis of drugs by
                                            fermentation and bio-transformation.
                                            4 - Legislative and economic considerations. Future perspectives.<\/p>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Marine Biotechnology I\",\"curricular_plan_cu_period\":\"2nd Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n

                                            1. Marine microbiology
                                              1.1 Introduction to marine microbiology
                                              1.2 Methods in marine microbiology
                                              1.3 Physiology of marine microorganisms
                                              1.4 Role of microorganisms in oceanic processes
                                              1.5 Genomics of marine microorganisms<\/li>
                                            2. Marine bioprospecting
                                              2.1 Isolation of marine natural products
                                              2.2 Bioactive and biomaterial compounds of the marine environment
                                              2.3 Assays for detection of enzymes and bioactive molecules<\/li>
                                            3. Sustainable growth of marine organisms
                                              3.1 Microalgae and macroalgae cultivation
                                              3.2 Cultivation of other marine organisms<\/li><\/ol>\\n\"}]},{\"curricular_plan_section_title\":\"3rd Year\",\"curricular_plan_cus\":[{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Bioinformatics\",\"curricular_plan_cu_period\":\"1st Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n

                                              Q1. Biological databases.
                                              P2. Introduction to algorithms in bioinformatics.
                                              P3. Sequence alignment, simple alignment, multiple alignment.
                                              Q4. Phylogeny
                                              Q4. Motif prediction and protein structure.
                                              P5. Gene prediction and genomic annotation.
                                              P6. Gene expression analysis<\/p>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Imunology and Biomedicine\",\"curricular_plan_cu_period\":\"1st Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n

                                              1. Introduction to immunology. Cells and organs of the immune system.<\/li>
                                              2. T cells and B cells: selection, maturation and activation.<\/li>
                                              3. Specific and non-specific defense mechanisms.
                                                3.1.Inflammatory response. Complement system. Interferon.
                                                3.2. Cellular immunity and humoral immunity.<\/li>
                                              4. Major histocompatibility complex: heredity, processing and antigen presentation.<\/li>
                                              5. Immunization.<\/li>
                                              6. Pathophysiology of the immune system: health and disease.
                                                6.1.Inflammation and anti-inflammatory mediators.
                                                6.2.Tolerance, hypersensitivity and autoimmunity; Immunodeficiencies.
                                                6.3. Transplantation and immune base of rejection.
                                                6.4.Cancer and immune system.
                                                6.5.Immunomodulation and immunotherapy.<\/li>
                                              7. Antigens and immunogens.<\/li><\/ol>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Animal Cell Technology\",\"curricular_plan_cu_period\":\"1st Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n
                                                1. Basic principles of animal cell and tissue culture.<\/li>
                                                2. Asepsis techniques and sterilization methods. Basic methods in cell and tissue culture: culture medium, subculture,
                                                  cell viability.
                                                  3.Culture of animal cells and tissues: Animal cell biology: metabolism; accession; proliferation; differentiation. Primary
                                                  culture, subcultures and cell lines. Equipment and culture media. Cryopreservation of animal cells. Experimental
                                                  methods: cell viability; cell proliferation; Apoptosis Tissue engineering.<\/li>
                                                3. Stem Cells<\/li>
                                                4. Multidrug Resistant Cells: Model Used to Test New Drugs<\/li>
                                                5. Animal models for tumor tissue induction.<\/li><\/ol>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Plant Cell Technology\",\"curricular_plan_cu_period\":\"1st Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n
                                                  1. Basic principles of plant cell and tissue culture: historical perspective and study methods in plant biotechnology.<\/li>
                                                  2. In vitro plant culture: totipotence and competence; vegetative multiplication, growth regulators, culture media and
                                                    environmental conditions of culture. Plant cloning - meristema propagation and organogenesis: meristema types,
                                                    objectives and limitations.<\/li>
                                                  3. Cell suspensions and somatic embryogenesis: types of embryogenesis, phases and induction. Pollen
                                                    embryogenesis and haploid production. Cell suspensions and production of secondary metabolites. Protoplasts and
                                                    somatic hybridization.<\/li>
                                                  4. Genetic manipulation and plant breeding. Genetically modified plants<\/li><\/ol>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Marine Biotechnology II\",\"curricular_plan_cu_period\":\"1st Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n
                                                    1. Seaweed Processes and Products<\/li>
                                                    2. Biomaterials<\/li>
                                                    3. Biosensors<\/li>
                                                    4. Biomarkers<\/li>
                                                    5. Biofuels<\/li>
                                                    6. Bioremediation Applications<\/li>
                                                    7. Biotechnological interventions in aquaculture<\/li><\/ol>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Biotechnology in Society\",\"curricular_plan_cu_period\":\"2nd Semester\",\"curricular_plan_cu_ects\":\"6\",\"curricular_plan_cu_duration\":\"60 h\",\"curricular_plan_cu_description\":\"\\n
                                                      1. Bioethics<\/li>
                                                      2. Communication in Science<\/li>
                                                      3. Biotechnology Entrepreneurship<\/li>
                                                      4. Intellectual Property<\/li>
                                                      5. Scientific Careers<\/li>
                                                      6. National and European Support Programs<\/li>
                                                      7. Regulatoty Framework<\/li>
                                                      8. Organization of study visit, lecture or scientific workshop<\/li><\/ol>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Interdisciplinary Project\",\"curricular_plan_cu_period\":\"2nd Semester\",\"curricular_plan_cu_ects\":\"9\",\"curricular_plan_cu_duration\":\"90 h\",\"curricular_plan_cu_description\":\"\\n
                                                        1. Theme selection and work team<\/li>
                                                        2. Research and experimental design<\/li>
                                                        3. Development of laboratory work<\/li>
                                                        4. Analysis and treatment of results<\/li>
                                                        5. Presentation and public discussion of the work developed<\/li><\/ol>\\n\"},{\"curricular_plan_cu_code\":\"\",\"curricular_plan_cu_title\":\"Project\/Intership\",\"curricular_plan_cu_period\":\"2nd Semester\",\"curricular_plan_cu_ects\":\"15\",\"curricular_plan_cu_duration\":\"\",\"curricular_plan_cu_description\":\"\\n

                                                          Project<\/p>\\n\\n\\n\\n

                                                          1. Research and update the state of the art on the theme
                                                            1.1. Literature search in the area of biotechnology
                                                            1.2. Prepare a monograph about the state of art of a given area of biotechnology<\/li>
                                                          2. Planning and development of a scientific project in Biotechnology
                                                            2.1. Definition of working hypotheses
                                                            2.2. Drafting and planning the steps in the development of a project
                                                            2.3. Organizing the work in the laboratory
                                                            2.4. Presentation of the preliminary scientific project in the form of seminars.
                                                            2.5. Planning of the experimental design.
                                                            2.6. Presentation of preliminary results of the scientific project in the form of a seminar.<\/li>
                                                          3. Writing the final report.
                                                            3.1. Writing a report with proper structure \/ formatting and discussion of the results obtained comparing them to the current state of the art.<\/li>
                                                          4. Presentation and discussion of final project
                                                            4.1. Defence and discussion of the written report and the oral presentation of the proposed project<\/li><\/ol>\\n\\n\\n\\n

                                                            Internship<\/p>\\n\\n\\n\\n

                                                            The Areas \/ Functions eligible for the internship are all related to the Biotechnology topics covered in the other
                                                            curricular units of the degree and which fit the requirements of the regulation of curricular and extracurricular
                                                            internships of ESTM (Regulation No. 1087\/2016).
                                                            According to each specific company, the registration \/ participation in the tasks should pay attention to the following
                                                            aspects:<\/p>\\n\\n\\n\\n

                                                            1. Research and update the state of the art on the topic proposed in the work plan.<\/li>
                                                            2. Requirements, challenges and particular aspects of the scope of activities performed<\/li>
                                                            3. Report writing<\/li><\/ol>\\n\"}]}]","custompostfields_course_testimonies":"","custompostfields_course_short_notice":"Vagas abertas para 2020\/2021","custompostfields_post-association_course_enrolment_link":{"opensInNewTab":true},"custompostfields_course_accreditation":"\n

                                                              State: Accreditated
                                                              N\u00ba years of Accredidation: 6
                                                              Date of Publication: 02\/09\/2021
                                                              A3ES Accreditation<\/a><\/p>\n","custompostfields_course_dges_registration":"\n

                                                              Link to Registration<\/a><\/p>\n","custompostfields_course_footer":""},"course_city":[286],"enrolment_state":[],"course_language":[55],"course_schedule":[15],"course_domain":[18],"course_school":[75],"course_type":[43],"course_tax":[],"_links":{"self":[{"href":"https:\/\/www.ipleiria.pt\/en\/wp-json\/wp\/v2\/course\/6185"}],"collection":[{"href":"https:\/\/www.ipleiria.pt\/en\/wp-json\/wp\/v2\/course"}],"about":[{"href":"https:\/\/www.ipleiria.pt\/en\/wp-json\/wp\/v2\/types\/course"}],"version-history":[{"count":20,"href":"https:\/\/www.ipleiria.pt\/en\/wp-json\/wp\/v2\/course\/6185\/revisions"}],"predecessor-version":[{"id":49334,"href":"https:\/\/www.ipleiria.pt\/en\/wp-json\/wp\/v2\/course\/6185\/revisions\/49334"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ipleiria.pt\/en\/wp-json\/wp\/v2\/media\/25046"}],"wp:attachment":[{"href":"https:\/\/www.ipleiria.pt\/en\/wp-json\/wp\/v2\/media?parent=6185"}],"wp:term":[{"taxonomy":"course_city","embeddable":true,"href":"https:\/\/www.ipleiria.pt\/en\/wp-json\/wp\/v2\/course_city?post=6185"},{"taxonomy":"enrolment_state","embeddable":true,"href":"https:\/\/www.ipleiria.pt\/en\/wp-json\/wp\/v2\/enrolment_state?post=6185"},{"taxonomy":"course_language","embeddable":true,"href":"https:\/\/www.ipleiria.pt\/en\/wp-json\/wp\/v2\/course_language?post=6185"},{"taxonomy":"course_schedule","embeddable":true,"href":"https:\/\/www.ipleiria.pt\/en\/wp-json\/wp\/v2\/course_schedule?post=6185"},{"taxonomy":"course_domain","embeddable":true,"href":"https:\/\/www.ipleiria.pt\/en\/wp-json\/wp\/v2\/course_domain?post=6185"},{"taxonomy":"course_school","embeddable":true,"href":"https:\/\/www.ipleiria.pt\/en\/wp-json\/wp\/v2\/course_school?post=6185"},{"taxonomy":"course_type","embeddable":true,"href":"https:\/\/www.ipleiria.pt\/en\/wp-json\/wp\/v2\/course_type?post=6185"},{"taxonomy":"course_tax","embeddable":true,"href":"https:\/\/www.ipleiria.pt\/en\/wp-json\/wp\/v2\/course_tax?post=6185"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}