In the present Master Program we aim at providing you with advanced training in the area of Biotechnology, with application to the Marine Resources, seeking to apply current knowledge of modern marine biology and biotechnology to the study, protection and development of marine resources.
1- Bioreactors a. The importance of bioreactors in marine biotechnology b. Revisions: kinetics of microbial growth, product formation and substrate consumption and mass balances c. Heat transfer and sterilization d. Measurement and main variables of control of a bioprocess e. Geometries and modes of bioreactor operation f. Bioreactors of non mechanical agitation g. Scale-Up h. Scale-Down i. Innovation in bioreactors and case studies: marine applications. 2- Biocatalysis a. Biocatalysis and biocatalysts – General properties and application examples. b. Enzyme kinetics – mechanisms, effect of temperature and pH, inhibition. c. Kinetics in multiphase systems. d. Enzymes and whole cell biocatalysts. e. Immobilization of biocatalysts. f. Biocatalysis in non-conventional media. g. Innovation in biocatalysis and case studies – biocatalysts of marine origin.
S1 Introduction to the separation and recovery processes of biomolecules. S2. General criteria for the selection of separation and recovery processes. S3. Methods for cell disruption, filtration and centrifugation. S4. Chromatographic and membrane based bioseparation methods. S5. Methods of extraction, precipitation, crystallization and drying. S6. Process integration and scale up.
1. Metabolic pathways common to all living organisms; 2. Enzyme kinetics, regulation models and balance of the metabolic pathways; 3. Catabolism of amino acids; 4. Lipid biosynthesis; 5. Biosynthesis of active compounds (eg terpenoids) with high biotechnological value in marine organisms.
P1. Common molecular biology techniques. 1.1 Isolation and purification of nucleic acids. Enzymatic manipulation of DNA. 1.2 Analysis of proteins. 1.3 Expression of proteins. 1.4 Bioinformatics. P2. Microbiological Techniques 2.1 Microbial diversity in the marine environment 2.2 Isolation, identification, growth and study of metabolic and physiological diversity of microorganisms 2.3. Phenotypic alternative methodologies in marine microbiology. P3. Characterization techniques used in Physical Chemistry. 3.1 Isolation and purification of polysaccharides in seaweed; 3.2 Characterization of polysaccharides by FT-IR; 3.3 Characterization of solutions of polysaccharides by viscometry.
Biomaterials – Biomaterials and Biological materials, (BM) Definitions and Classification Polymers and composites – Biomaterials from marine origin, (BOM) Quitin e quitosan, Collagen, Alginates, Carrageen’s, Biosílics Other polymers from marine origin Biosensors – Biosensor types (BS) – Materials e detection techniques and biosensor examples (MB) – Health, environment and marine applications for biosensors (AB)
2009209 – Seminars on Bio-Entrepreneurship
1.1. From idea to business 1.2. Preliminary Feasibility Study 1.3. And financing options available 1.4. Technology-based entrepreneurship
2.1. The Biotechnology Cluster 2.2. The Cluster of marine resources 2.3. Networks of Bioentrepreneurship 2.4. Networks of innovation in biotechnology
Strategic thinking Bioentrepreneurship
3.1. Perception of opportunity 3.2. Aggregation of intellectual capital 3.3. Human and technological capital 3.4. Economic and financial capital
Leverage business opportunities:
4.1. Synergies and strategic alliances 4.2. Spin-Offs and the importance of linking the academia and industry 4.3. Legal aspects and support the biotechnology industry and marine resources 5.Business valuation and analysis of investment projects in the field of Biotechnology. 6. Case-studies
Importance of biotechnology in aquaculture and in its economy.
Inbreeding and genetic variability in aquaculture.
Population Genetics: hybridisation and breeding, selection, mutations and genetic drift.
Polyploidy in aquatic species.
Application of genetic engineering in aquaculture: DNA construct, methods of gene transfer into fish;2009210 – Biotechnology in Aquaculture detection of integration and transgene expression, results of genetic engineering technology in fish, the regulation of GMO; ethical aspects.
Genetic markers to identify phenotypic characteristics in aquaculture
DNA vaccines and their use in aquaculture.
Molecular tools for diagnosis of viral and bacterial diseases.
A. Pollutants, contaminants and environmental risks in the marine environment. B. Requirements for pollutant degradation. C. Methods of pollution treat. D. Abiotic processes in the degradation of pollutants. E. Marine organisms in bioremediation process a. microorganisms b. algae F. Bioremediation technologies a. in situ b. ex situ
Holders of an academic bachelor’s degree following a 1st cycle of studies organized according to the principles of the Bologna process in the area of Marine Biology and Biotechnology, and related areas;
Holders of a bachelor’s degree that is recognized as meeting the objectives of a degree by the Scientific-Technical Council of ESTM in the area of marine biology and biotechnology or related areas;
Holders of an academic, scientific or professional curricula who is recognized as attesting the capacity to carry out this cycle of studies by the Scientific-Technical Council of ESTM.
English Language Proficiency.
State: Accredited Nº of years of Accreditation: 6 Date of Publication: 22-02-2017 A3ES Accreditation